 | Anno Spin-Off 1 | Anno 1701: Dawn of Discovery | Game Card | Disney Interactive Studios | Keen Games | Nintendo DS |   | .png) |
 | Band Hero | Band Hero | Game Card | Activision | Vicarious Visions | Nintendo DS | | .png) |
 | Dr. Kawashima's Brain Training 2 | More Brain Training from Dr. Kawashima: How Old Is Your Brain? | Game Card | Nintendo | Nintendo System Development | Nintendo DS | | |
 | FIFA 2011 | FIFA 11 | Game Card | EA Sports | Exient Entertainment | Nintendo DS | | .png) |
 | Grand Theft Auto 4.3 | Grand Theft Auto: Chinatown Wars | Game Card | Rockstar Games | Rockstar Leeds
Rockstar North | Nintendo DS | | .png) |
 | Guitar Hero: On Tour 1 | Guitar Hero: On Tour | Game Card | Activision
RedOctane | Vicarious Visions | Nintendo DS | | .png) |
 | Harry Potter 6 | Harry Potter and the Half-Blood Prince | Game Card | Electronic Arts | EA Bright Light | Nintendo DS | | .png) |
 | Kingdom Hearts 1.3 | Kingdom Hearts 358/2 Days | Game Card | Square Enix | Square Enix
h.a.n.d. | Nintendo DS | | .png) |
 | Legend of Zelda 15 | The Legend of Zelda: Spirit Tracks | Game Card | Nintendo | Nintendo Entertainment Analysis & Development | Nintendo DS | | .png) |
 | LEGO Harry Potter 1 | LEGO Harry Potter: Years 1-4 | Game Card | Warner Bros. Interactive Entertainment | TT Fusion | Nintendo DS | | .png) |
 | LEGO Harry Potter 2 | LEGO Harry Potter: Years 5-7 | Game Card | Warner Bros. Interactive Entertainment | TT Fusion | Nintendo DS | | |
 | LEGO Lord of the Rings | LEGO The Lord of the Rings | Game Card | Warner Bros. Interactive Entertainment | TT Fusion | Nintendo DS | | |
 | LEGO Star Wars 4 | LEGO Star Wars III: The Clone Wars | Game Card | LucasArts | TT Fusion | Nintendo DS | | |
 | LEGO Star Wars 3 | LEGO Star Wars: The Complete Saga | Game Card | LucasArts | TT Fusion | Nintendo DS |  |  |
 | Madagascar: Escape 2 Africa | Madagascar: Escape 2 Africa | Game Card | Activision | Griptonite Games | Nintendo DS | | |
 | Myst 1 | Myst | Game Card | Midway Games | Hoptile Research | Nintendo DS | | |
 | Over The Hedge | Over The Hedge | Game Card | Activision | Vicarious Visions | Nintendo DS | | |
 | Pokémon Remake 2 | Pokémon SoulSilver Version | Game Card | Nintendo | Game Freak
Creatures | Nintendo DS | | |
 | Professor Layton 1 | Professor Layton and the Curious Village | Game Card | Nintendo | Level-5 | Nintendo DS | | |
 | Professor Layton 2 | Professor Layton and the Pandora's Box | Game Card | Nintendo | Level-5 | Nintendo DS | | |
 | Simpsons 16 | The Simpsons Game | Game Card | Electronic Arts | Griptonite Games | Nintendo DS | | |
 | SpongeBob 14 | SpongeBob's Truth or Square | Game Card | THQ | Altron | Nintendo DS | | |
 | Super Mario Handheld 3 | New Super Mario Bros. | Game Card | Nintendo | Nintendo Entertainment Analysis & Development | Nintendo DS | | |
 | Super Monkey Ball 5 | Super Monkey Ball Touch & Roll | Game Card | SEGA | Amusement Vision | Nintendo DS | | |
 | Tamagotchi Connection: Corner Shop 3 | Tamagotchi Connection: Corner Shop 3 | Game Card | Namco Bandai Games | NanaOn-Sha | Nintendo DS | | |
 | Tony Hawk's Spin Off 2 | Tony Hawk's Motion | Game Card | Activision | Creat Studio | Nintendo DS | | |
 | WALL-E | WALL·E | Game Card | THQ | Helixe | Nintendo DS | | .png) |
 | Broken Sword 1.2 | Broken Sword: Shadow of the Templars | Game Card | Ubisoft | Revolution Software | Nintendo DS | | |
 | Diddy Kong Racing DS | Diddy Kong Racing DS | Game Card | Nintendo | Rare | Nintendo DS | | |
 | Kirby: Mouse Attack | Kirby: Mouse Attack | Game Card | Nintendo | HAL Laboratory
Flagship
Natsume | Nintendo DS | | |
 | Nintendogs: Lab & Friends | Nintendogs: Lab & Friends | Game Card | Nintendo | Nintendo Entertainment Analysis & Development | Nintendo DS | | |
 | Pokémon 4 | Pokémon Pearl Version | Game Card | Nintendo | Game Freak | Nintendo DS | | |
 | Professor Layton 3 | Professor Layton and the Lost Future | Game Card | Nintendo | Level-5 | Nintendo DS | | |
 | Professor Layton 4 | Professor Layton and the Spectre's Call | Game Card | Nintendo | Level-5 | Nintendo DS | | |
 | Cars Mater-National Championship | Cars Mater-National Championship | Game Card | THQ | Tantalus Interactive | Nintendo DS | | |
 | Iron Man | Iron Man | Game Card | SEGA | Artificial Mind and Movement | Nintendo DS | | |
 | Super Mario 5 | Super Mario 64 DS | Game Card | Nintendo | Nintendo Entertainment Analysis & Development | Nintendo DS | | |
| Mario & Sonic Olympic 2010 | Mario & Sonic at the Olympic Winter Games | Game Card | SEGA | SEGA Sports Japan | Nintendo DS | | |
 | Juiced 2 | Juiced 2: Hot Import Nights | Game Card | THQ | Juice Games | Nintendo DS | | |
 | James Pond 2 | James Pond 2: Codename: RoboCod | Game Card | Play It! | Vectordean | Nintendo DS | | |
 | Junior Brain Trainer | Junior Brain Trainer | Game Card | Global Star Software | Sanuk Games | Nintendo DS | | |
 | Scurge: Hive | Scurge: Hive | Game Card | SouthPeak Interactive | Orbital Media | Nintendo DS | | |
 | Crosswords DS | Crosswords DS | Game Card | Nintendo | Nuevo Retro Games | Nintendo DS | | |
 | Custom Robo Arena | Custom Robo Arena | Game Card | Nintendo | Noise | Nintendo DS | | |
 | Pokémon Ranger | Pokémon Ranger | Game Card | Nintendo | HAL Laboratory
Creatures | Nintendo DS | | |
 | Prince of Persia The Sands of Time 4 | Battles of Prince of Persia | Game Card | Ubisoft | Ubisoft Montréal | Nintendo DS | | |
 | Doctor Who: Evacuation Earth | Doctor Who: Evacuation Earth | Game Card | BBC Multimedia | Asylum Entertainment | Nintendo DS | | |
 | Brothers in Arms 4 | Brothers in Arms DS | Game Card | Ubisoft | Gameloft
Gearbox Software | Nintendo DS | | .png) |
 | Sims 2 Console 2 | The Sims 2: Pets | Game Card | Electronic Arts | Full Fat | Nintendo DS | | |
 | Call of Duty 4.1 | Call of Duty 4: Modern Warfare | Game Card | Activision | n-Space | Nintendo DS | | |
| Scooby-Doo! Who's Watching Who? | Scooby-Doo! Who's Watching Who? | Game Card | THQ | Human Soft | Nintendo DS | | |
 | Inazuma Eleven | Inazuma Eleven | Game Card | Nintendo | Level-5 | Nintendo DS | | |
| Harry Potter 7.2 | Harry Potter and the Deathly Hallows: Part 2 | Game Card | Electronic Arts | Full Fat | Nintendo DS | | |
 | Hotel Dusk: Room 215 | Hotel Dusk: Room 215 | Game Card | Nintendo | CING | Nintendo DS | | |
.jpg) | Super Mario Handheld 3 | New Super Mario Bros. | Game Card | Nintendo | Nintendo Entertainment Analysis & Development | Nintendo DS | | |
| Professor Brainmaniac | Professor Brainmaniac | Game Card | White Park Bay Software | Frontline Studios | Nintendo DS | | |
 | Vegas Casino | Vegas Casino | Game Card | Crave Entertainment | NEKO Entertainment | Nintendo DS | | |
| Thrillville 2 | Thrillville: Off the Rails | Game Card | LucasArts | DC Studios | Nintendo DS | | |
| 4 Game Pack | Clue
Mouse Trap
Perfection
Aggravation | Game Card | Destination Software | DSI Games | Nintendo DS | | |
 | Tom Clancy's Splinter Cell 3.1 | Tom Clancy's Splinter Cell Chaos Theory | Game Card | Ubisoft | Gameloft Divertissements | Nintendo DS | | |
 | LEGO Pirates of the Caribbean: The Video Game | LEGO Pirates of the Caribbean: The Video Game | Game Card | Disney Interactive Studios | TT Fusion | Nintendo DS | | |
 | Sonic Handheld 11 | Sonic Rush Adventure | Game Card | SEGA | DIMPS
Sonic Team | Nintendo DS | | |
| 4 Game Fun Pack | Monopoly
Boggle
Yahtzee
Battleship | Game Card | Atari | Sensory Sweep | Nintendo DS | | |
| Pokémon Mystery Dungeon 1 | Pokémon Mystery Dungeon: Blue Rescue Team | Game Card | Nintendo | Chunsoft | Nintendo DS | | |
| Legend of Spyro 2 | The Legend of Spyro: The Eternal Night | Game Card | Sierra Entertainment | Amaze Entertainment | Nintendo DS | | |
| Super Princess Peach | Super Princess Peach | Game Card | Nintendo | Nintendo
TOSE | Nintendo DS | | |
| Dragon Quest 9 | Dragon Quest IX: Sentinels of the Starry Skies | Game Card | Nintendo | Level-5 | Nintendo DS | | .png) |
 | 42 All-Time Classics | 42 All-Time Classics | Game Card | Nintendo | Agenda | Nintendo DS | | |
| Toy Story 3 | Toy Story 3 | Game Card | Disney Interactive Studios | n-Space | Nintendo DS | | |
| Ratatouille | Ratatouille | Game Card | THQ | Helixe | Nintendo DS | | |
| Mario Party DS | Mario Party DS | Game Card | Nintendo | Hudson Soft | Nintendo DS | | |
| WarioWare 6 | WarioWare: Do It Yourself | Game Card | Nintendo | Intelligent Systems
Nintendo Software Planning & Development | Nintendo DS | | |
| Zubo | Zubo | Game Card | Electronic Arts | EA Bright Light | Nintendo DS | | |
| WALL-E | WALL·E | Game Card | THQ | Helixe | Nintendo DS | | |
| LEGO Battles | LEGO Battles | Game Card | Warner Bros. Interactive Entertainment | Hellbent Games | Nintendo DS | | |
| Pokémon Mystery Dungeon 2 | Pokémon Mystery Dungeon: Explorers of Time | Game Card | Nintendo | Chunsoft | Nintendo DS | | |
| Mario & Luigi 3 | Mario & Luigi Bowser's Inside Story | Game Card | Nintendo | AlphaDream | Nintendo DS | | |
 | Polarium | Polarium | Game Card | Nintendo | Mitchell Corporation | Nintendo DS | | |
| Spider-Man 30 | Spider-Man: Web of Shadows | Game Card | Activision | Griptonite Games | Nintendo DS | | |
| LEGO Star Wars 2 | LEGO Star Wars II: The Original Trilogy | Game Card | LucasArts | Amaze Entertainment | Nintendo DS | | |
| Final Fantasy 12.2 | Final Fantasy XII: Revenant Wings | Game Card | Square Enix | Think & Feel
Square Enix | Nintendo DS | | |
| Thrillville 2 | Thrillville: Off the Rails | Game Card | LucasArts | DC Studios | Nintendo DS | | |
| Exit DS | Exit DS | Game Card | Square Enix | Moss | Nintendo DS | | |
| Beat the Intro | Beat the Intro | Game Card | Mindscape | Route 1 Games | Nintendo DS | | |
| Overlord Minions | Overlord Minions | Game Card | Codemasters | Climax Studios | Nintendo DS | | |
| Nintendo DS Lite Browser | Nintendo DS Lite Browser | Game Card | Nintendo | Nintendo | Nintendo DS | | |
| Nacho Libre | Nacho Libre | Game Card | Majesco Entertainment | Budcat Creations | Nintendo DS | | |
| Who Wants to be a Millionaire? | Who Wants to be a Millionaire? | Game Card | Ubisoft | Ludia | Nintendo DS | | |
| LEGO Rock Band | LEGO Rock Band | Game Card | MTV Games
Warner Bros. Interactive Entertainment | Backbone Entertainment
Harmonix Music Systems
Traveller's Tales | Nintendo DS | | |
| G.I. Joe: The Rise of Cobra | G.I. Joe: The Rise of Cobra | Game Card | Electronic Arts | Backbone Entertainment | Nintendo DS | | |
| Chronicles of Narnia 2 | The Chronicles of Narnia: Prince Caspian | Game Card | Disney Interactive Studios | Fall Line Studios | Nintendo DS | | |
| Rayman 2 | Rayman DS | Game Card | Ubisoft | Ubisoft Shanghai | Nintendo DS | | |
| MicroMachines V4 | MicroMachines V4 | Game Card | Codemasters | Supersonic Software | Nintendo DS | | |
| Chronicles of Narnia 1 | The Chronicles of Narnia: The Lion, The Witch and The Wardrobe | Game Card | Buena Vista Games | Griptonite Games | Nintendo DS | | |
| Star Wars Episode 3: Revenge of the Sith | Star Wars: Episode III: Revenge of the Sith | Game Card | Ubisoft | Ubisoft Montréal | Nintendo DS | | |
| Animal Crossing 2 | Animal Crossing: Wild World | Game Card | Nintendo | Nintendo Entertainment Analysis & Development | Nintendo DS | | |
| SpongeBob 10 | SpongeBob Squarepants: Creature from the Krusty Krab | Game Card | THQ | WayForward Technologies | Nintendo DS | | |
| LEGO Indiana Jones 1 | LEGO Indiana Jones: The Original Adventures | Game Card | LucasArts | TT Fusion | Nintendo DS | | |
| Mario Hoops 3 On 3 | Mario Hoops 3 On 3 | Game Card | Nintendo | Square Enix | Nintendo DS | | |
| Shaun the Sheep | Shaun the Sheep | Game Card | D3 Publishing | Art | Nintendo DS | | |
| Legend of Zelda 14 | The Legend of Zelda: Phantom Hourglass | Game Card | Nintendo | Nintendo Entertainment Analysis & Development | Nintendo DS | | |
| Disney Friends | Disney Friends | Game Card | Disney Interactive Studios | Amaze Entertainment | Nintendo DS | | |
| Worms 10 | Worms: Open Warfare 2 | Game Card | THQ | Team 17 Software
Two Tribes | Nintendo DS | | |
| Hannah Montana | Hannah Montana | Game Card | Buena Vista Games | DC Studios | Nintendo DS | | |
| Pokémon 4 | Pokémon Diamond Version | Game Card | Nintendo | Game Freak | Nintendo DS | | |
| High School Musical: Makin' The Cut | High School Musical: Makin' The Cut | Game Card | Disney Interactive Studios | Artificial Mind & Movement | Nintendo DS | | |
| Nintendogs: Chihuahua & Friends | Nintendogs: Chihuahua & Friends | Game Card | Nintendo | Nintendo Entertainment Analysis & Development | Nintendo DS | | |
| Harry Potter 5 | Harry Potter and the Order of the Phoenix | Game Card | Electronic Arts | EA Bright Light | Nintendo DS | | |
| Rayman Raving Rabbids 3 | Rayman Raving Rabbids: TV Party | Game Card | Ubisoft | Ubisoft Paris | Nintendo DS | | |
| Deal or No Deal | Deal or No Deal | Game Card | Destination Software | Gravity-I | Nintendo DS | | |
| Settlers | The Settlers | Game Card | Ubisoft | Blue Byte | Nintendo DS | | |
| 100 Classic Books | 100 Classic Books | Game Card | Nintendo | Easy Interactive | Nintendo DS | | |
| Red Bull BC One | Red Bull BC One | Game Card | Playlogic International | Smackdown Productions | Nintendo DS | | |
| Telly Addicts | Telly Addicts | Game Card | Ubisoft | Slam! Games | Nintendo DS | | |
| DreamWorks Super Star Kartz | DreamWorks Super Star Kartz | Game Card | Activision | Virtuos | Nintendo DS | | |
| Spider-Man 34 | Spider-Man: Edge of Time | Game Card | Activision | Other Ocean Interactive | Nintendo DS | | |
| Cate West: The Vanishing Files | Cate West: The Vanishing Files | Game Card | Destineer | Gamenauts
Menara Games | Nintendo DS | | |
| Teenage Mutant Ninja Turtles 33 | TMNT | Game Card | Ubisoft | Ubisoft Quebec | Nintendo DS | | |
| James Bond 22 | GoldenEye: Rogue Agent | Game Card | EA Games | EA Tiburon
n-Space | Nintendo DS | | |
| Peter Jackson's King Kong: The Official Game of the Movie | Peter Jackson's King Kong: The Official Game of the Movie | Game Card | Ubisoft | Ubisoft Casablanca | Nintendo DS | | |
| Rooms: The Main Building | Rooms: The Main Building | Game Card | Hudson Soft | HandMade Game | Nintendo DS | | |
| Asphalt 1 | ` Asphalt: Urban GT | Game Card | Gameloft | Gameloft Montréal | Nintendo DS | | |
| Mario & Sonic Olympic 2008 | Mario & Sonic at the Olympic Games | Game Card | Nintendo | SEGA Sports Japan | Nintendo DS | | |
| Puzzler World 2012 | Puzzler World 2012 | Game Card | Ubisoft | ideas Pad | Nintendo DS | | |
| Puzzler World 2 | Puzzler World 2 | Game Card | Ubisoft | ideas Pad | Nintendo DS | | |
| Diabolik: The Original Sin | Diabolik: The Original Sin | Game Card | Black Bean Games | Artematica | Nintendo DS | | |
| TouchMaster | TouchMaster | Game Card | Midway Games | Hijinx Studios | Nintendo DS | | |
| High School Musical 2: Work This Out | High School Musical 2: Work This Out | Game Card | Disney Interactive Studios | Artificial Mind and Movement | Nintendo DS | | |
| Rock Revolution | Rock Revolution | Game Card | Konami Digital Entertainment | HB Studios Multimedia | Nintendo DS | | |
| Scene it? Twilight | Scene it? Twilight | Game Card | Konami Digital Entertainment | Screenlife | Nintendo DS | | |
| Professor Kageyama's Maths Training: The Hundred Cell Calculation Method | Professor Kageyama's Maths Training: The Hundred Cell Calculation Method | Game Card | Nintendo | Jupiter
Rokumendo | Nintendo DS | | |
| SEGA Casino | SEGA Casino | Game Card | SEGA | TOSE | Nintendo DS | | |
| Tim Power: Handyman | Tim Power: Handyman | Game Card | Ubisoft | Magic Pockets | Nintendo DS | | |
| Kung Zhu | Kung Zhu | Game Card | Activision | 1st Playable Productions | Nintendo DS | | |
| Chrono Trigger | Chrono Trigger | Game Card | Square Enix | Square | Nintendo DS | | |
| Hidden Mysteries: Buckingham Palace | Hidden Mysteries: Buckingham Palace | Game Card | GameMill Entertainment | Gamemill Entertainment
Gunnar Games | Nintendo DS | | |
| Shaun the Sheep | Shaun the Sheep | Game Card | D3Publisher | ART | Nintendo DS | | |
| Trauma Center 1 | Trauma Center: Under the Knife | Game Card | Nintendo | Atlus | Nintendo DS | | |
| Paint by DS | Paint by DS | Game Card | Mercury Games | Ertain | Nintendo DS | | |
| Imagine: Fashion Designer | Imagine: Fashion Designer | Game Card | Ubisoft | Lexis Numérique | Nintendo DS | | |
| Imagine: Modern Dancer | Imagine: Modern Dancer | Game Card | Ubisoft | Lexis Numérique | Nintendo DS | | |
| Littlest Pet Shop: Winter | Littlest Pet Shop: Winter | Game Card | Electronic Arts | EA Salt Lake | Nintendo DS | | |
| Animaniacs: Lights, Camera, Action! | Animaniacs: Lights, Camera, Action! | Game Card | Ignition Entertainment | Warthog | Nintendo DS | | |
| Junior Brain Trainer 2 | Junior Brain Trainer 2 | Game Card | GSP | Sanuk Games | Nintendo DS | | |
| Spyro: Shadow Legacy | Spyro: Shadow Legacy | Game Card | Sierra Entertainment | Amaze Entertainment | Nintendo DS | | |
| Petz Fashion: Dogz & Catz | Petz Fashion: Dogz & Catz | Game Card | Ubisoft | Powerhead Games | Nintendo DS | | |
