 | Triple Play 96 | Triple Play 96 | Cartridge | EA Sports | Extended Play Productions | SEGA Genesis |  |  |
 | Two Crude Dudes | Two Crude Dudes | Cartridge | Data East Corporation | Data East | SEGA Genesis | | |
| Chakan: The Forever Man | Chakan: The Forever Man | Cartridge | SEGA | Extended Play Productions | SEGA Genesis | | |
 | Ayrton Senna's Super Monaco GP 2 | Ayrton Senna's Super Monaco GP II | Cartridge | SEGA | SEGA | Mega Drive |   | |
 | California Games | California Games | Cartridge | SEGA | Epyx | Mega Drive | | |
 | DecapAttack | DecapAttack | Cartridge | SEGA | Vic Tokai | Mega Drive | | |
 | Ecco the Dolphin | Ecco the Dolphin | Cartridge | SEGA | Novotrade Software | Mega Drive | | |
 | FIFA 1995 | FIFA Soccer 95 | Cartridge | Electronic Arts | Extended Play Productions | Mega Drive | |  |
 | Golden Axe 2 | Golden Axe II | Cartridge | SEGA | SEGA AM7 | Mega Drive | | |
 | Gunship | Gunship | Cartridge | U.S Gold | Probe Software | Mega Drive | | |
 | Indiana Jones 5 | Indiana Jones and the Last Crusade: The Action Game | Cartridge | U.S Gold | Tiertex Design Studios | Mega Drive | | |
 | James Bond 11 | James Bond 007: The Duel | Cartridge | Domark Software | The Kremlin | Mega Drive | | |
 | Jungle Strike | Jungle Strike | Cartridge | Electronic Arts | High Score | Mega Drive | | |
 | Lotus Turbo Challenge 3 | Lotus II: RECS | Cartridge | Electronic Arts | Magnetic Fields | Mega Drive | | |
 | Mega Games 1 | Mega Games 1 | Cartridge | SEGA | SEGA | Mega Drive | | |
 | Lotus Turbo Challenge 2 | Lotus Turbo Challenge | Cartridge | Electronic Arts | Magnetic Fields | Mega Drive | | |
 | Mega Games 2 | Mega Games 2 | Cartridge | SEGA | SEGA | Mega Drive | | |
 | PGA Tour 1992 | PGA Tour Golf II | Cartridge | Electronic Arts | Polygames | Mega Drive | | |
 | Phelios | Phelios | Cartridge | Namco | Namco | Mega Drive | | |
 | Puggsy | Puggsy | Cartridge | Psygnosis | Traveller's Tales | Mega Drive | | |
 | Road Rash | Road Rash | Cartridge | Electronic Arts | Electronic Arts | Mega Drive | | |
 | Simpsons 04 | Krusty's Super Fun House | Cartridge | Acclaim Entertainment | Audiogenic Software | Mega Drive | | |
 | Sonic 01 | Sonic the Hedgehog | Cartridge | SEGA | Sonic Team | Mega Drive | | |
 | Sonic 02 | Sonic the Hedgehog 2 | Cartridge | SEGA | Sonic Team | Mega Drive | | |
 | Sonic 04 | Sonic the Hedgehog 3 | Cartridge | SEGA | Sonic Team | Mega Drive | | |
 | Sonic 05 | Sonic & Knuckles | Cartridge | SEGA | Sonic Team | Mega Drive | | |
 | Sonic Other 1 | Sonic the Hedgehog: Spinball | Cartridge | SEGA | Polygames
SEGA Technical Institute | Mega Drive | | |
 | Space Harrier 2 | Space Harrier II | Cartridge | SEGA | SEGA | Mega Drive | | |
 | Taz-Mania | Taz-Mania | Cartridge | SEGA | Recreational Brainware | Mega Drive | | |
 | ToeJam & Earl 1.1 | ToeJam & Earl | Cartridge | SEGA | Johnson Voorsanger Productions | Mega Drive | | |
 | Turbo Outrun | Turbo Outrun | Cartridge | SEGA | SEGA AM2 | Mega Drive | | |
 | Urban Strike | Urban Strike | Cartridge | Electronic Arts | The Edge
Foley Hi-Tech Systems | Mega Drive | | |
 | Virtua Fighter 2.2 | Virtua Fighter 2 | Cartridge | SEGA | Gaibrain | Mega Drive | | |
 | Wrestle War | Wrestle War | Cartridge | SEGA | SEGA | Mega Drive | | |
 | WWE WrestleMania 04 | WWF Super Wrestlemania | Cartridge | Flying Edge | Sculptured Software | Mega Drive | | |
 | Aquatic Games Starring James Pond and the Aquabats | Aquatic Games Starring James Pond and the Aquabats | Cartridge | Electronic Arts | Millennium Interactive | Mega Drive | | |
 | Bonkers | Disney's Bonkers | Cartridge | SEGA | SEGA Interactive Development Division | Mega Drive | | |
 | Toy Story | Disney's Toy Story | Cartridge | SEGA | Traveller's Tales | Mega Drive | | |
 | FIFA 1997 | FIFA 97 | Cartridge | Electronic Arts | Extended Play Productions | Mega Drive | | |
 | Lion King | The Lion King | Cartridge | Virgin Interactive Entertainment | Westwood Studios | Mega Drive | | |
 | Mega Games 3 | Mega Games 3 | Cartridge | SEGA | SEGA | Mega Drive | | |
 | Mickey Mania | Mickey Mania | Cartridge | Sony Imagesoft | Traveller's Tale | Mega Drive | | |
 | Virtua Racing | Virtua Racing | Cartridge | SEGA | SEGA AM2 | Mega Drive | | |
 | QuackShot Starring Donald Duck | QuackShot Starring Donald Duck | Cartridge | SEGA | SEGA | Mega Drive | | |
 | Another World | Another World | Cartridge | SEGA | Delphine Software | Mega Drive | | |
 | Double Dragon 3 | Double Dragon III: The Arcade Game | Cartridge | Flying Edge | East Technology | Mega Drive | | |
 | Mega Lo Mania | Mega Lo Mania | Cartridge | Virgin Interactive Entertainment | Sensible Software | Mega Drive | | |
 | Altered Beast | Altered Beast | Cartridge | SEGA | SEGA | Mega Drive | | |
 | Cool Spot | Cool Spot | Cartridge | Virgin Interactive Entertainment | Virgin Games | Mega Drive | | |
 | ToeJam & Earl 2.1 | ToeJam & Earl in Panic on Funkotron | Cartridge | SEGA | Johnson Voorsanger Productions | Mega Drive | | |
 | Dragon's Fury | Dragon's Fury | Cartridge | Tengen | Compile | Mega Drive | | |
 | Simpsons 2 | The Simpsons: Bart vs. the Space Mutants | Cartridge | Flying Edge | Imagineering | Mega Drive | | |
 | Spider-Man 07 | Marvel's Spider-Man | Cartridge | SEGA | Technopop | Mega Drive | | |
 | Fantasia | Fantasia | Cartridge | SEGA | Infogrames Entertainment | Mega Drive | | |
 | Taz in Escape from Mars | Taz in Escape from Mars | Cartridge | SEGA | HeadGames | Mega Drive | | |
 | Shinobi 2 | The Revenge of Shinobi | Cartridge | SEGA | SEGA | Mega Drive | | |
 | Dick Tracy | Dick Tracy | Cartridge | SEGA | SEGA | Mega Drive | | |
 | Michael Jackson's Moonwalker | Michael Jackson's Moonwalker | Cartridge | SEGA | SEGA | Mega Drive | | |
 | Home Alone | Home Alone | Cartridge | SEGA | Brian A. Rice | Mega Drive | | |
 | Streets of Rage | Streets of Rage | Cartridge | SEGA | SEGA | Mega Drive | | |
 | Jurassic Park 10 | Jurassic Park: Rampage Edition | Cartridge | SEGA | BlueSky Software | Mega Drive | |  |
 | Batman Film 5 | Batman Returns | Cartridge | SEGA | Malibu Interactive | Mega Drive | | |
 | PGA Tour 1991 | Mega Games 3 | Cartridge | Electronic Arts | Sterling Silver Software | Mega Drive | | |
 | FIFA 1993 | FIFA International Soccer | Cartridge | Electronic Arts | Extended Play Productions | Mega Drive | | |
 | Ballz | Ballz | Cartridge | Accolade | PF Magic | Mega Drive | | |
 | James Pond 2: Codename: RoboCod | James Pond 2: Codename: RoboCod | Cartridge | Electronic Arts | Vectordean | Mega Drive | | |
| RoboCop Versus The Terminator | RoboCop Versus The Terminator | Cartridge | Virgin Interactive Entertainment | Virgin Games | Mega Drive | | |
| Marble Madness | Marble Madness | Cartridge | Electronic Arts | Atari Games | Mega Drive | | |
| Terminator | The Terminator | Cartridge | Virgin Games | Probe Software | Mega Drive | | |
| Zoop | Zoop | Cartridge | Viacom New Media | Hookstone | Mega Drive | | |
| MTV's Beavis and Butt-Head: The Game | MTV's Beavis and Butt-Head: The Game | Cartridge | Viacom New Media | Radical Entertainment | Mega Drive | | |
| Worms | Worms | Cartridge | Ocean Software | Team 17 Software | Mega Drive | | |
| Earthworm Jim | Earthworm Jim | Cartridge | Virgin Interactive Entertainment | Shiny Entertainment | Mega Drive | | |
| Mortal Kombat | Mortal Kombat | Cartridge | Arena Entertainment | Midway Games | Mega Drive | | |
| Pinocchio | Pinocchio | Cartridge | Disney Interactive Studios | Virgin Studios London | Mega Drive | | |
| Disney's TaleSpin | Disney's TaleSpin | Cartridge | SEGA | SEGA Interactive Development Division | Mega Drive | | |
| Cannon Fodder | Cannon Fodder | Cartridge | Virgin Interactive Entertainment | Sensible Software | Mega Drive | | |
| Dynamite Headdy | Dynamite Headdy | Cartridge | SEGA | Treasure | Mega Drive | | |
| F1 | F1 | Cartridge | Domark Software | Lankhor | Mega Drive | | |
| Sonic 02 | Sonic the Hedgehog 2 | Cartridge | SEGA | Sonic Team | Mega Drive |  | |
| Flashback | Flashback | Cartridge | U.S. Gold | Delphine Software | Mega Drive | | |
| Dynamite Duke | ダイナマイト デューク Dainamaito Dūku | Cartridge | SEGA | Seibu Kaihatsu | Mega Drive | | |
| WWE Programming 6 | WWF Raw | Cartridge | Acclaim Entertainment | Sculptured Software | Mega Drive | | |
| Mortal Kombat 2 | Mortal Kombat II | Cartridge | Acclaim Entertainment | Midway | Mega Drive | | |
| Dragon's Fury | Dragon's Fury | Cartridge | Tengen | Compile | Mega Drive | | |
| Two Crude Dudes | Two Crude Dudes | Cartridge | Data East | Data East | Mega Drive | | |
| World of Illusion Starring Mickey Mouse and Donald Duck | World of Illusion Starring Mickey Mouse and Donald Duck | Cartridge | SEGA | SEGA AM7 | Mega Drive | | |
| Paperboy | Paperboy | Cartridge | Tengen | Atari | Mega Drive | | |
| Ms. Pac-Man | Ms. Pac-Man | Cartridge | Tengen | Midway
General Computer | Mega Drive | | |
